Why the study?
Does nifedipine potentiate cardiopulmonary baroreflex control of sympathetic nerve activity in healthy humans?
Population
26 healthy human subjects (23 in main study, 3 in graded LBNP), mean age 23 +/- 1 years
Comparison
Nifedipine 10 mg sublingual or nitroprusside… vs Placebo sublingual (n=5)
Design
Other
Follow-up
20 minutes after administration
Authors
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Nifedipine may potentiate cardiopulmonary baroreflex sympathetic control in healthy humans; leaves open relevance to patients or outcomes.
Does nifedipine potentiate cardiopulmonary baroreflex control of sympathetic nerve activity in healthy humans?
Nifedipine, but not nitroprusside, potentiates cardiopulmonary baroreflex control of sympathetic nerve activity in healthy humans.
Ferguson et al. (1989) studied this question.
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