Why the study?
Does irbesartan improve survival and hemodynamics in a rat model of chronic heart failure?
Does irbesartan improve survival and hemodynamics in a rat model of chronic heart failure?
Long-term AT1 receptor blockade with irbesartan dose-dependently improves survival and hemodynamics in a rat model of chronic heart failure.
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Extends preclinical support for AT1 blockade in heart failure; leaves open translation to human therapy.
Christine Richer (1999) studied this question.
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