Why the study?
Do ebastine and terfenadine affect electrocardiographic parameters in conscious dogs and cats?
Do ebastine and terfenadine affect electrocardiographic parameters in conscious dogs and cats?
Terfenadine demonstrates proarrhythmic potential by prolonging QT/QTc intervals in conscious dogs and cats, whereas ebastine does not induce such electrocardiographic changes.
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Terfenadine may increase arrhythmia risk in dogs and cats; leaves open human translation and ebastine cardiac safety.
Kii et al. (2003) studied this question.
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