Why the study?
Does irbesartan provide greater and longer-lasting angiotensin II antagonism compared to valsartan and losartan in healthy men?
Does irbesartan provide greater and longer-lasting angiotensin II antagonism compared to valsartan and losartan in healthy men?
At standard starting doses, irbesartan provides more potent and longer-lasting angiotensin II receptor blockade than valsartan or losartan in healthy men.
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May favor irbesartan for sustained AT1 blockade in select patients; extends head-to-head pharmacodynamic data among ARBs in humans.
G BELZ (1999) studied this question.
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