Prosthetic Valvular Endocarditis
Why the study?
What factors and treatment strategies (antimicrobial therapy and/or surgery) improve survival in patients with prosthetic valvular endocarditis?
Population
n=48 patients with infected prosthetic cardiac valves
Design
Cohort
Authors
Discussion
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Member takes
Overview
Medical therapy may suffice initially in prosthetic valve endocarditis; leaves open optimal surgical timing criteria.
Structured PICO
What factors and treatment strategies (antimicrobial therapy and/or surgery) improve survival in patients with prosthetic valvular endocarditis?
P
Population
n=48 patients with infected prosthetic cardiac valves (from a total of 1,236 patients implanted during 1960-1972)
I
Intervention
Antimicrobial therapy (various agents and dosage schedules) with or without surgical replacement (reoperation)
O
Outcome
Patient survivalhard clinical
Medical treatment alone can be effective for prosthetic valvular endocarditis, but prompt surgical replacement is indicated if antimicrobial therapy fails to eradicate the infection.
Cite This Study
Slaughter et al. (1973) studied this question.