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October 1, 1987Circulation ResearchOpen Access

Synchronous occurrence of spontaneous localized calcium release from the sarcoplasmic reticulum generates action potentials in rat cardiac ventricular myocytes at normal resting membrane potential.

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Authors

MCM. C. CapogrossiIstituto Dermopatico dell'ImmacolataSHSteven R. HouserHeart Failure & TransplantABAnthony BahinskiTeradyne (United States)

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Implication

Localized Ca²⁺ events may trigger arrhythmias if synchronized; leaves open their role in human arrhythmogenesis.

Key Points

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Cite This Study

Capogrossi et al. (1987) studied this question.

synapsesocial.com/papers/6a709e45e36a167817e26f5chttps://doi.org/10.1161/01.res.61.4.498
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Also Consider

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  1. 1Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibres.1976 · 406 citations
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  4. 4An oscillatory current in sheep cardiac Purkinje fibers.1981 · 91 citations
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