Why the study?
Does the diagnostic yield of surveillance endomyocardial biopsy for detecting cardiac allograft rejection differ between the modern mycophenolate era and the early azathioprine era in heart transplant patients?
Population
182 consecutive heart transplantation patients who survived to their first endomyocardial biopsy, undergoing…
Comparison
Surveillance endomyocardial biopsy in the modern… vs Surveillance endomyocardial biopsy in the early…
Design
Cohort
Follow-up
up to 36 months
Authors
Loading...
May question routine surveillance EMB beyond 6 months in modern era; leaves open optimal monitoring strategies pending prospective trials.
Does the diagnostic yield of surveillance endomyocardial biopsy for detecting cardiac allograft rejection differ between the modern mycophenolate era and the early azathioprine era in heart transplant patients?
The diagnostic yield of surveillance endomyocardial biopsy for detecting cardiac allograft rejection in asymptomatic heart transplant patients has significantly decreased in the modern era, questioning its routine use beyond 6 months post-transplant.
Shah et al. (2015) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: