What question did this study set out to answer?

This study aims to evaluate left ventricular dyssynchrony in patients with left ventricular hypertrophy, comparing hypertrophic cardiomyopathy and hypertensive heart disease.

May 14, 2007Echocardiography

Hypertrophic Cardiomyopathy Is Associated with More Severe Left Ventricular Dyssynchrony than Is Hypertensive Left Ventricular Hypertrophy

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Why the study?

Is hypertrophic cardiomyopathy associated with more severe left ventricular dyssynchrony than hypertensive heart disease?

Population

58 subjects, including 43 patients with left ventricular hypertrophy and 15 age-matched controls.

Comparison

2D speckle tracking imaging for assessment of… vs Hypertensive heart disease and age-matched…

Design

Cross-sectional

Authors

TNToshiki NagakuraTane General Hospital MTMasaaki TakeuchiCardiac Imaging HYHidetoshi YoshitaniHeart Rhythm Society

Discussion

Member takes

Implication

Greater LV dyssynchrony in HCM may heighten risk versus HHD; leaves open whether imaging refines stratification or therapy in LVH.

Key Points

This study aims to evaluate left ventricular dyssynchrony in patients with left ventricular hypertrophy, comparing hypertrophic cardiomyopathy and hypertensive heart disease.
43 patients with left ventricular hypertrophy and 15 age-matched controls were analyzed.
2D speckle tracking imaging measured radial and circumferential strain.
Time intervals for strain peaks were calculated to assess LV dyssynchrony.
Regional radial strain in HCM patients was significantly less than in HHD (P < 0.001).
HCM patients showed longer time intervals for Trs-18SD and Tcs-18SD compared to controls and HHD (P < 0.001).
Greater LV dyssynchrony in HCM may contribute to increased cardiovascular risks.

Structured PICO

Is hypertrophic cardiomyopathy associated with more severe left ventricular dyssynchrony than hypertensive heart disease?

Population

58 subjects, including 43 patients with left ventricular hypertrophy (20 with hypertrophic cardiomyopathy [HCM], 23 with hypertensive heart disease [HHD]) and 15 age-matched controls.

Intervention

2D speckle tracking imaging for assessment of left ventricular dyssynchrony

Comparator

Hypertensive heart disease and age-matched healthy controls

Outcome

Left ventricular dyssynchrony assessed by the standard deviation of time to peak radial strain (Trs-18SD) and circumferential strain (Tcs-18SD) in 18 segmentssurrogate

Hypertrophic cardiomyopathy is associated with significantly more severe left ventricular dyssynchrony and reduced regional strain compared to hypertensive heart disease, which may contribute to adverse cardiovascular outcomes.

Cite This Study

Nagakura et al. (2007) studied this question.

synapsesocial.com/papers/6a70aa9fb27f158178277746 https://doi.org/10.1111/j.1540-8175.2007.00458.x

Topics

Hypertrophic cardiomyopathy Hypertension management

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Hypertrophic Cardiomyopathy Is Associated with More Severe Left Ventricular Dyssynchrony than Is Hypertensive Left Ventricular Hypertrophy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Hypertrophic Cardiomyopathy Is Associated with More Severe Left Ventricular Dyssynchrony than Is Hypertensive Left Ventricular Hypertrophy

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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