Why the study?
Does nitrendipine, cilazapril, or their combination improve blood pressure, renal hemodynamics, and proteinuria in hypertensive patients with chronic renal failure?
Population
11 hypertensive patients with chronic renal failure
Comparison
Nitrendipine, cilazapril, or the combination of… vs Placebo
Design
RCT, randomized, double-blind
Follow-up
1 week
Authors
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Supports adding cilazapril to nitrendipine for greater BP and albuminuria reduction in hypertensive chronic renal failure; extends monotherapy data to combination regimens.
Does nitrendipine, cilazapril, or their combination improve blood pressure, renal hemodynamics, and proteinuria in hypertensive patients with chronic renal failure?
The combination of nitrendipine and cilazapril effectively lowers blood pressure and reduces albuminuria in hypertensive patients with chronic renal failure.
Kloke et al. (1990) studied this question.
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