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April 17, 2012Interactive Cardiovascular and Thoracic SurgeryOpen Access

The incidence of MACCE was significantly higher in the mid-wall LGE group compared with absent or infarct LGE groups (25% vs. 0% vs. 5%, P = 0.014).

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Why the study?

Does the presence of myocardial late gadolinium enhancement on CMR predict postoperative outcomes in patients with aortic stenosis undergoing aortic valve replacement?

Population

63 patients with aortic stenosis undergoing cardiovascular magnetic resonance using the late gadolinium…

Comparison

Presence of mid-wall or infarct patterns of… vs Absence of myocardial late gadolinium…

Design

Cohort, Independent observers blinded to all clinical data categorized LGE…

Follow-up

30 days for MACCE/complications, up to 2 years for mortality

Authors

CQCesare QuartoMDMarc R. DweckTMTimothy Murigu

Discussion

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Overview

May identify higher-risk AVR patients; leaves open whether CMR-guided stratification improves outcomes.

Structured PICO

Does the presence of myocardial late gadolinium enhancement on CMR predict postoperative outcomes in patients with aortic stenosis undergoing aortic valve replacement?

P
Population
63 patients with aortic stenosis undergoing cardiovascular magnetic resonance using the late gadolinium enhancement technique within 1 year of subsequent aortic valve replacement.
I
Intervention
Presence of mid-wall or infarct patterns of myocardial late gadolinium enhancement (LGE) on CMR
C
Comparator
Absence of myocardial late gadolinium enhancement (LGE) on CMR
O
Outcome
30-day mortality, major adverse cardiac and cerebrovascular events (MACCE), and postoperative complicationshard clinical

Mid-wall late gadolinium enhancement on CMR is associated with increased perioperative risk, including MACCE and heart block, in patients undergoing aortic valve replacement for aortic stenosis.

Cite This Study

Quarto et al. (2012) studied this question.

synapsesocial.com/papers/6a70ab50a528af2d65c3ab2ehttps://doi.org/10.1093/icvts/ivs098
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