Why the study?
Does cilazapril improve resistance artery structure compared to atenolol in essential hypertensive patients?
Population
17 essential hypertensive patients
Comparison
Cilazapril for 2 years vs Atenolol (beta-blocker) for 2 years
Design
RCT, randomly assigned
Follow-up
2 years
Authors
Loading...
Cilazapril but not atenolol reverses resistance artery remodeling in hypertension; confirms class-specific vascular effects in long-term RCT.
Does cilazapril improve resistance artery structure compared to atenolol in essential hypertensive patients?
Long-term treatment with the ACE inhibitor cilazapril, but not the beta-blocker atenolol, normalizes resistance artery structure in essential hypertensive patients.
Schiffrin et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: