March 16, 2010Journal of Hypertension
Determinants of blood pressure variability in youth: at the roots of hypertension
Why the study?
What are the longitudinal determinants of blood pressure variability in youth?
Population
Ethnically mixed cohort of 641 young subjects
Design
Editorial
Follow-up
up to 15 years
Authors
Discussion
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Implication
May warrant closer BP monitoring in at-risk youth; hypothesis-generating for CV risk reduction strategies.
Structured PICO
What are the longitudinal determinants of blood pressure variability in youth?
P
Population
Ethnically mixed cohort of 641 young subjects (approximately equal numbers of European-Americans and African-Americans)
I
Intervention
Repeated (up to 12) 24-h ambulatory blood pressure monitoring sessions
O
Outcome
Determinants of 24-h blood pressure variabilitysurrogate
The determinants of blood pressure variability in youth, including age, male sex, absolute BP levels, obesity, and low socioeconomic status, closely mirror established predictors of high cardiovascular risk.
Limitations
- Noninvasive intermittent ambulatory BP monitoring has limited reproducibility
- Lacks normal reference values
- Affected by individual behavior during monitoring time
- Discontinuous low-frequency BP sampling limits accuracy in assessing fast BP changes
Cite This Study
Schillaci et al. (2010) studied this question.