Population
Mathematical model of sinoatrial node electrical activity based on whole cell recordings from enzymatically…
Design
Preclinical
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Model supports ionic mechanisms in sinoatrial node simulations; leaves open human translation and therapeutic testing.
A novel mathematical model of the sinoatrial node demonstrates that complex chronotropic responses to vagal stimulation arise from inherent ionic mechanisms.
Dokos et al. (1996) studied this question.
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