Population
Right ventricular endocardial tissue isolated from six dogs
Comparison
New pacing protocol to change diastolic interval… vs Currently used pacing protocols to determine…
Design
Preclinical
Authors
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Questions standard restitution protocols in arrhythmia models; leaves open clinical translation pending human studies.
Sequential and explicit control of diastolic intervals reveals that action potential duration restitution exhibits multimodal behavior, suggesting unimodal predictions may be inappropriate.
Wu et al. (2004) studied this question.
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