Why the study?
Does adrenalectomy alter baroreflex sensitivity and blood pressure in patients with primary aldosteronism?
Population
135 subjects, including 30 patients with primary aldosteronism, 60 patients with essential hypertension, and…
Comparison
Removal of an adrenal adenoma in 25 patients… vs Pre-operative values; essential hypertension and…
Design
Cohort
Follow-up
3 to 4 weeks
Authors
Loading...
Adrenalectomy may reduce baroreflex sensitivity in primary aldosteronism; leaves open effects on outcomes and requires prospective confirmation.
Does adrenalectomy alter baroreflex sensitivity and blood pressure in patients with primary aldosteronism?
Hypertension due to primary aldosteronism is characterized by an increased baroreceptor-heart rate reflex gain, which is significantly reduced following adrenalectomy.
Munakata et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: