Why the study?
What factors predict the required dose of warfarin in elderly patients?
Population
80 patients over 65 years old with satisfactory coagulation control with Warfarin
Design
Cross-sectional
Authors
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May support age- and urea-guided warfarin dosing in elderly patients; leaves open prospective validation before practice change.
What factors predict the required dose of warfarin in elderly patients?
Age and blood urea levels are important predictors of warfarin dose requirements in elderly patients, suggesting careful monitoring is needed in those with high urea.
James Eccles (1975) studied this question.
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