Why the study?
Does pimobendan improve hemodynamics and clinical status in patients with class III-IV stable congestive heart failure?
Population
9 patients in class III-IV stable congestive heart failure
Design
Case_series
Follow-up
28 days
Authors
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Supports hemodynamic improvement in severe HF case report; hypothesis-generating with safety concerns requiring RCTs.
Does pimobendan improve hemodynamics and clinical status in patients with class III-IV stable congestive heart failure?
Pimobendan improves hemodynamics and clinical status in severe heart failure, but the occurrence of sudden death raises significant safety concerns regarding arrhythmogenicity.
Hagemeijer et al. (1989) studied this question.
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