Why the study?
Does genipin fixation with decellularization and detoxification reduce calcification in bovine pericardial tissues compared to glutaraldehyde fixation?
Does genipin fixation with decellularization and detoxification reduce calcification in bovine pericardial tissues compared to glutaraldehyde fixation?
Genipin fixation combined with decellularization, organic solvent treatment, and detoxification significantly reduces calcification of bovine pericardium compared to conventional glutaraldehyde fixation in a rabbit model.
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Genipin fixation may attenuate bioprosthetic calcification; leaves open translation beyond rabbit models.
Lim et al. (2011) studied this question.
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