Why the study?
Is the ACE gene I/D polymorphism associated with Parkinson's disease risk?
Population
5 studies including 606 Parkinson's disease cases and 708 controls
Comparison
ACE gene I/D polymorphism vs Controls without Parkinson's disease
Design
Meta-analysis
Authors
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ACE I/D polymorphism shows no PD risk association; leaves open other renin-angiotensin genetic contributions to neurodegeneration.
Is the ACE gene I/D polymorphism associated with Parkinson's disease risk?
This meta-analysis found no evidence of an association between the ACE gene I/D polymorphism and the risk of Parkinson's disease.
Su et al. (2013) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: