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January 6, 2017Journal of Hypertension

Associations of risk factors in childhood with arterial stiffness 26 years later

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Why the study?

Does high blood pressure in childhood increase the risk of long-term arterial stiffness and hypertension in adulthood?

Population

4,623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi, China, surveyed in 1987 and…

Comparison

High blood pressure in childhood vs Normal blood pressure in childhood

Design

Cohort

Follow-up

26 years

Authors

CCChao ChuGeneral / Preventive / LipidsYDYi DaiGuangxi Medical UniversityJMJianjun MuPreventive Cardiology

Discussion

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Implication

Childhood high BP tracking was associated with adult arterial stiffness; leaves open whether early intervention alters vascular trajectories.

Structured PICO

Does high blood pressure in childhood increase the risk of long-term arterial stiffness and hypertension in adulthood?

P
Population
4,623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi, China, surveyed in 1987 and followed up 26 years later.
I
Intervention
High blood pressure in childhood (SBP ≥ 75th percentile across three measurements in 1987, 1989, and 1992)
C
Comparator
Normal blood pressure in childhood (SBP < 50th percentile)
O
Outcome
Brachial-ankle pulse wave velocity (baPWV) and incidence of hypertension at 26-year follow-upsurrogate

Higher systolic blood pressure in childhood is associated with an increased risk of long-term arterial stiffness and hypertension in adulthood.

Cite This Study

Chu et al. (2017) studied this question.

synapsesocial.com/papers/6a70db1e35aa2c282ce22fe6https://doi.org/10.1097/hjh.0000000000001242

Topics

Hypertension management
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Also Consider

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  5. 5Higher glucose, insulin and insulin resistance (HOMA-IR) in childhood predict adverse cardiovascular risk in early adulthood: the Pune Children’s Study2015 · 61 citations