Why the study?
Does plasma cardiac troponin I concentration differentiate cats with moderate to severe hypertrophic cardiomyopathy from healthy cats?
Population
53 cats, comprising 20 cats with moderate to severe hypertrophic cardiomyopathy and 33 healthy control cats.
Comparison
Measurement of plasma cardiac troponin I… vs Healthy control cats
Design
Preclinical
Authors
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Supports cTnI for feline HCM detection; hypothesis-generating for clinical translation pending prospective validation.
Does plasma cardiac troponin I concentration differentiate cats with moderate to severe hypertrophic cardiomyopathy from healthy cats?
Plasma cardiac troponin I is a highly sensitive and specific biomarker for detecting ongoing myocardial damage in cats with moderate to severe hypertrophic cardiomyopathy.
Herndon et al. (2002) studied this question.
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