Why the study?
Does recombinant tissue plasminogen activator improve successful thrombolysis compared to streptokinase in patients undergoing local intra-arterial thrombolysis?
Population
167 patients undergoing local intra-arterial thrombolysis
Comparison
Recombinant tissue plasminogen activator (rtPA) vs Streptokinase
Design
Cohort
Authors
Loading...
rtPA may associate with higher success and faster lysis than streptokinase; hypothesis-generating, needs RCTs before practice change.
Does recombinant tissue plasminogen activator improve successful thrombolysis compared to streptokinase in patients undergoing local intra-arterial thrombolysis?
Recombinant tissue plasminogen activator is more effective and faster than streptokinase for local intra-arterial thrombolysis, without an increased risk of bleeding.
Lonsdale et al. (1992) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: