Population
Preclinical models (rats, guinea pigs, cats, dogs) and humans
Design
Review
Authors
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Supports bisoprolol consideration in hypertension; extends selectivity data but leaves outcome comparisons open.
Bisoprolol is characterized as an optimized beta-blocker due to its high beta-1 selectivity and favorable pharmacokinetic profile.
Haeusler et al. (1985) studied this question.
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