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March 1, 2010Tumori Journal

A Preliminary Audit Experience of Surgery for Rectal Cancer after Neoadjuvant Chemoradiation Therapy

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Why the study?

Does neoadjuvant chemoradiation therapy influence postoperative morbidity and mortality in patients with lower and medium rectal cancer?

Population

42 patients who underwent elective surgical resection for lower and medium rectal cancer

Comparison

Neoadjuvant chemoradiation therapy and… vs Primary surgical treatment

Design

Cohort

Follow-up

30-day

Authors

GUGiampaolo UgoliniGRG. RosatiIMIsacco Montroni

Discussion

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Overview

Neoadjuvant chemoradiation therapy prior to rectal cancer surgery does not significantly increase postoperative morbidity or mortality compared to primary surgery.

Structured PICO

Does neoadjuvant chemoradiation therapy influence postoperative morbidity and mortality in patients with lower and medium rectal cancer?

P
Population
42 patients who underwent elective surgical resection for lower and medium rectal cancer
I
Intervention
Neoadjuvant chemoradiation therapy and consequent surgical resection
C
Comparator
Primary surgical treatment
O
Outcome
30-day mortality and morbidity rates compared to P-POSSUM and CR-POSSUM expected rateshard clinical

Neoadjuvant chemoradiation therapy prior to rectal cancer surgery does not significantly increase postoperative morbidity or mortality compared to primary surgery.

Cite This Study

Ugolini et al. (2010) studied this question.

synapsesocial.com/papers/6a70e5ec6ceb2bbd16e00734https://doi.org/10.1177/030089161009600212
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