Why the study?
Does a low-dose warfarin induction regimen improve anticoagulation control compared to the modified Fennerty regimen in elderly inpatients?
Population
120 age-stratified elderly inpatients (aged 65-75 years and >75 years)
Comparison
New low-dose warfarin induction regimen vs Modified Fennerty regimen
Design
RCT, Age-stratified, randomized
Follow-up
8 days
Authors
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Supports low-dose induction over modified Fennerty in elderly inpatients; extends RCT evidence for safer warfarin initiation.
Does a low-dose warfarin induction regimen improve anticoagulation control compared to the modified Fennerty regimen in elderly inpatients?
A low-dose warfarin induction regimen in elderly inpatients results in more time in the therapeutic range and fewer instances of over-anticoagulation compared to the modified Fennerty regimen.
J Gedge (2000) studied this question.
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