Population
In vitro endothelial cell monolayers
Comparison
Angiopoietin-1 vs Control
Design
Preclinical
Authors
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Ang-1 stabilizes endothelium in animal models; leaves open translation to human vascular therapies.
Angiopoietin-1 acts as an antipermeability and anti-inflammatory agent in vitro by strengthening endothelial cell junctions and inhibiting leukocyte transmigration.
Gamble et al. (2000) studied this question.
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