The influence of muscle mass, strength, fatigability and blood flow on exercise capacity in cachectic and non-cachectic patients with chronic heart failure
Why the study?
The influence of age, skeletal muscle function, and peripheral blood flow on exercise capacity in chronic heart failure patients is controversial, possibly due to variations in skeletal muscle atrophy.
Population
16 cachectic and 39 non-cachectic male chronic heart failure patients of similar age and ejection fraction
Comparison
Cachectic vs non-cachectic chronic heart failure patients
Design
Cross-sectional study
Authors
Discussion
Loading...
Member takes
Implication
Peak blood flow may limit exercise capacity in cachectic HF; leaves open whether flow-targeted interventions improve outcomes.
Structured PICO
P
Population
55 male chronic heart failure patients (16 cachectic, 39 non-cachectic) of similar age and ejection fraction.
O
Outcome
Predictors of exercise capacity (peak oxygen consumption)surrogate
The predictors of exercise capacity shift from age and muscle strength in non-cachectic heart failure patients to peak blood flow in those with cardiac cachexia.
Cite This Study
Anker et al. (1997) studied this question.