Why the study?
Does hemodialysis reduce dabigatran's anticoagulant effect and prevent abnormal bleeding in a patient requiring emergent cardiac surgery?
Population
1 patient with heart failure and atrial fibrillation on dabigatran 150 mg twice daily, admitted for…
Design
Case_report
Authors
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May support hemodialysis for dabigatran reversal in urgent surgery; hypothesis-generating case report requiring prospective validation.
Does hemodialysis reduce dabigatran's anticoagulant effect and prevent abnormal bleeding in a patient requiring emergent cardiac surgery?
Hemodialysis may be an effective strategy to rapidly reduce the anticoagulant effects of dabigatran prior to emergent cardiac surgery.
Wanek et al. (2012) studied this question.