Why the study?
Does antihypertensive treatment improve left ventricular systolic and diastolic function and mass in patients with essential hypertension?
Population
29 untreated patients with essential hypertension, comprising 13 with mild hypertension and 16 with moderate…
Comparison
Antihypertensive treatment vs Baseline (before treatment)
Design
Cohort
Follow-up
mean 1.8 +/- 0.3 years in group I and 2.0 +/- 0.4 years in…
Authors
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LV mass regression may be limited to moderate-severe hypertension; leaves open whether diastolic changes improve outcomes in randomized trials.
Does antihypertensive treatment improve left ventricular systolic and diastolic function and mass in patients with essential hypertension?
Antihypertensive treatment improves diastolic filling parameters across hypertension severities and induces regression of left ventricular hypertrophy in moderate to severe hypertension, without altering intrinsic contractility.
Yoshitomi et al. (1997) studied this question.
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