Why the study?
What is the persistence rate with antihypertensive therapy among newly treated middle-aged patients with essential hypertension?
Population
21,011 patients aged 50-64 years with essential hypertension, newly treated with antihypertensive agents…
Comparison
Antihypertensive therapy vs Diuretics (used as the reference class)
Design
Cohort
Follow-up
up to 3.5 years
Authors
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Persistence declines rapidly and is lowest with diuretics; leaves open whether class-specific strategies improve adherence in essential hypertension.
What is the persistence rate with antihypertensive therapy among newly treated middle-aged patients with essential hypertension?
Persistence with antihypertensive therapy declines significantly over the first 3 years of treatment, with diuretics having the lowest persistence rates among antihypertensive classes.
Sylvie Perreault (2005) studied this question.
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