Why the study?
Does an auxiliary transplanted heart effectively act as a temporary left heart bypass in an experimental model?
Does an auxiliary transplanted heart effectively act as a temporary left heart bypass in an experimental model?
An auxiliary transplanted heart can effectively function as a temporary left heart bypass to maintain systemic circulation during experimental left ventricular failure or fibrillation.
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Supports experimental feasibility of auxiliary heart as temporary left bypass; leaves open clinical translation.
(1) A technique for connecting an auxiliary heart, so that it acts as a temporary left heart bypass, is described. (2) It is shown that the transplanted heart takes over the systemic circulation when the recipient aorta is cross-clamped. (3) The transplanted heart will take over the whole circulation when the recipient heart has ventricular fibrillation. (4) Left heart bypass with a transplanted heart is suggested for treating experimental left ventricular failure.Artificial maintenance of the circulation by means of left heart bypass has been studied for several years (2, 3, 4, 7). Satisfactory application of the procedure is, however, limited by technical difficulties.The aim of this investigation was to carry out a left heart bypass by means of a transplanted heart. This method might be used for long periods, provided that the immunological problems can be solved.
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Johansson et al. (1967) studied this question.
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