Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma
Population
10 normotriglyceridemic men
Comparison
Oral fat load (postprandial state) vs Fasting state
Design
Cross-sectional
Follow-up
postprandial period
Authors
Discussion
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Member takes
Implication
These compositional differences do not change clinical lipid assessment; leaves open distinct atherogenic roles pending prospective studies.
Structured PICO
P
Population
10 normotriglyceridemic men
I
Intervention
Oral fat load (postprandial state)
C
Comparator
Fasting state
O
Outcome
Apolipoprotein (E, C-I, C-II, C-III) and lipid (triglycerides, phospholipids, cholesterol) composition in Sf 60-400 and Sf 20-60 subfractions of VLDL and chylomicron remnantssurrogate
Specific alterations in apolipoprotein and lipid composition of chylomicron remnants and VLDL during alimentary lipemia suggest different metabolic routes and roles in atherogenesis.
Cite This Study
Björkegren et al. (1998) studied this question.