Why the study?
Is the AT1R/A1166C polymorphism associated with essential hypertension in the Japanese general population?
Population
1,207 Japanese rural residents of Ohasama Town
Comparison
AT1R/A1166C polymorphism (genotypes AA, AC, CC) vs Comparison among AT1R genotypes (AA, AC, CC)
Design
Cohort
Authors
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AT1R genotyping does not aid hypertension risk assessment in untreated Japanese adults; leaves open contributions from other genetic variants.
Is the AT1R/A1166C polymorphism associated with essential hypertension in the Japanese general population?
The AT1R/A1166C polymorphism is not a major genetic predisposing factor for essential hypertension in the Japanese population.
Sugimoto et al. (2004) studied this question.
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