Key result
The presence of the AT1 C1166 allele was not significantly associated with adjusted daytime systolic blood pressure (129.1 vs 127.9 mmHg, p=0.32) or other clinical parameters of hypertension.
Why the study?
Does the AT1 A/C1166 gene polymorphism affect ambulatory blood pressure and cardiovascular disease prevalence in a general Japanese population?
Cross-Sectional (n=802)
No
Does the AT1 A/C1166 gene polymorphism affect ambulatory blood pressure and cardiovascular disease prevalence in a general Japanese population?
Absolute Event Rate: 129.1% vs 127.9%
p-value: p=0.32
The AT1 A/C1166 gene polymorphism is not significantly associated with ambulatory blood pressure levels or cardiovascular disease prevalence in the general Japanese population.
No takes yet. Share an insight, caveat, or question.
No link to ambulatory BP in this Japanese cohort; leaves open ethnic or phenotypic specificity of AT1 C1166 polymorphism.
Kikuya et al. (2003) conducted a cross-sectional in Hypertension (n=802). AT1 A/C1166 gene polymorphism (C allele) vs. AA genotype was evaluated on Adjusted daytime systolic blood pressure (p=0.32). The presence of the AT1 C1166 allele was not significantly associated with adjusted daytime systolic blood pressure (129.1 vs 127.9 mmHg, p=0.32) or other clinical parameters of hypertension.
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