Why the study?
Is the Gbeta3-C825T variant associated with the presence of essential hypertension and higher ambulatory blood pressure levels?
Population
479 white patients with established essential hypertension and 1000 normotensive gender- and age-matched…
Comparison
Presence of the Gbeta3-C825T variant (T allele) vs Non-T carriers and normotensive controls
Design
Case-control
Authors
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Supports modest association with hypertension susceptibility but not severity; hypothesis-generating and requires prospective validation.
Is the Gbeta3-C825T variant associated with the presence of essential hypertension and higher ambulatory blood pressure levels?
The Gbeta3-C825T variant is associated with an increased risk of essential hypertension but does not correlate with more severe blood pressure levels in established disease.
Beige et al. (1999) studied this question.
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