Why the study?
Does the T825 variant of the G protein beta3 subunit gene increase susceptibility to essential hypertension in a Japanese population?
Population
1,424 Japanese individuals recruited at a single institution.
Comparison
Presence of the T825 variant of the G protein… vs Absence of the T825 variant (C allele)
Design
Case-control
Authors
Loading...
Does not support C825T testing in Japanese patients; challenges prior associations reported in white populations and requires replication.
Does the T825 variant of the G protein beta3 subunit gene increase susceptibility to essential hypertension in a Japanese population?
The T825 variant of the G protein beta3 subunit gene does not appear to be a major susceptibility locus for essential hypertension in the Japanese population, contrasting with previous findings in white populations.
Kato et al. (1998) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: