Why the study?
Does plasma diluted thrombin time improve the accuracy of monitoring direct thrombin inhibitors compared to aPTT in patient samples with baseline coagulation abnormalities?
Does plasma diluted thrombin time improve the accuracy of monitoring direct thrombin inhibitors compared to aPTT in patient samples with baseline coagulation abnormalities?
Plasma diluted thrombin time is a viable and more accurate alternative to aPTT for monitoring direct thrombin inhibitors, particularly in patients with baseline aPTT abnormalities such as lupus inhibitors.
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Plasma diluted thrombin time may aid direct thrombin inhibitor monitoring amid coagulation abnormalities; hypothesis-generating from Level 5 data and needs clinical validation.
Love et al. (2007) studied this question.
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