Why the study?
Does carotid intima media thickness differ between nonhypertensive type 2 diabetics, hypertensives, and normal controls in Nigerian Africans?
Does carotid intima media thickness differ between nonhypertensive type 2 diabetics, hypertensives, and normal controls in Nigerian Africans?
There is a nonsignificant trend toward increased carotid IMT in Nigerian patients with diabetes or hypertension compared to normal controls, indicating a shared burden of cardiovascular risk.
Nonsignificant IMT trend in Nigerian diabetics and hypertensives should not change practice; leaves open ethnic differences in subclinical atherosclerosis.
As part of a larger study of cardiovascular risk factors in nonhypertensive type 2 diabetes patients, we subjected a cohort of diabetics to B mode ultrasonography of the carotid artery to measure the intima media thickness (IMT) and compared it with values in hypertensives and apparently normal controls matched reasonably for gender and age. All groups were comparable in terms of age and gender representation. The mean (SD) of carotid IMT right and left was 0.94 mm (0.12), 0.94 mm (0.16); 0.93 mm (0.21), 0.93 mm (0.15); 0.91 mm (0.17), 0.91 mm (0.13) for diabetic, hypertensive, and normal groups, respectively. There was a nonsignificant tendency to raised IMT for the disease groups from the normal ones. Diabetic and hypertensive Nigerians are equally burdened by cardiovascular disease risk factors. Apparently normal subjects have a reasonable degree of burden suggesting the need to evaluate them for other traditional and emerging risk factors.
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Okeahialam et al. (2011) studied this question.
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