Population
Isolated perfused rabbit atria
Comparison
Atrial distension combined with electrical… vs Atrial pacing without distension, distension…
Design
Preclinical
Authors
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May inform ANP release mechanisms during pacing; leaves open translation to human atrial physiology and clinical relevance.
The principal stimulus for ANP secretion in response to atrial pacing and distension is the length shortening of atrial myocytes, driven by pacing frequency.
Cho et al. (1991) studied this question.
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