Population
Retrograde-perfused isolated rabbit hearts
Comparison
Distension of the left atrium via a fluid-filled… vs Distension of the right atrium via a…
Design
Preclinical
Authors
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Left atrial ANF dominance in rabbits challenges rat findings; leaves open interspecies translation and human relevance.
In isolated rabbit hearts, the left atrium contains and releases more atrial natriuretic factor in response to distension than the right atrium, contrasting with right atrial dominance seen in rats.
Synhorst et al. (1988) studied this question.
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