Why the study?
Does increased dietary NaCl intake alter cardiac volume receptor reflex control of efferent renal sympathetic nerve activity in borderline hypertensive rats?
Population
Borderline hypertensive rats (BHR) from age 4 to 16 weeks
Comparison
8% NaCl dietary intake vs 1% NaCl dietary intake
Design
Preclinical
Follow-up
12 weeks (from age 4 to 16 weeks)
Authors
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High salt may alter cardiac volume receptor reflexes in borderline hypertensive rat models; leaves open relevance to human salt-sensitive hypertension.
Does increased dietary NaCl intake alter cardiac volume receptor reflex control of efferent renal sympathetic nerve activity in borderline hypertensive rats?
High dietary salt intake in borderline hypertensive rats exaggerates the cardiac volume receptor reflex control of efferent renal sympathetic nerve activity.
DiBona et al. (1993) studied this question.