Why the study?
Do plasma concentrations of beta-thromboglobulin and platelet factor 4 correlate with platelet survival in patients with coronary artery disease?
Population
91 studies of patients with coronary artery disease
Design
Cross-sectional
Authors
Loading...
May indicate platelet activation in CAD; hypothesis-generating for biomarker validation in prospective studies.
Do plasma concentrations of beta-thromboglobulin and platelet factor 4 correlate with platelet survival in patients with coronary artery disease?
Plasma concentrations of betaTG and PF4 correlate with shortened platelet survival, suggesting they may serve as indicators of in vivo platelet activation and involvement in coronary artery disease.
Doyle et al. (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: