January 1, 1986Kitakantou igaku/Kitakantō IgakuOpen Access

STUDY ON THE RELATIONSHIP BETWEEN PLATELET LIFE-SPAN AND PLASMA CONCENTRATION OF β-THROMBOGLOBULIN (β-TG) OR PLATELET FACTOR 4 (PF-4) IN VARIOUS DISEASE GROUPS

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Why the study?

Is there a correlation between platelet life-span and plasma concentrations of β-TG or PF-4 in patients with various diseases compared to healthy controls?

Population

97 individuals, comprising 28 normal subjects and 69 patients with various diseases.

Design

Cross-sectional

Authors

MNMotoo NagasakaGunma University

Discussion

Member takes

Implication

May support β-TG/PF-4 as markers of platelet consumption; leaves open prospective outcome validation in IHD.

Structured PICO

Is there a correlation between platelet life-span and plasma concentrations of β-TG or PF-4 in patients with various diseases compared to healthy controls?

Population

97 individuals, comprising 28 normal subjects and 69 patients with various diseases (9 essential hypertension, 12 diabetes mellitus, 6 malignant tumor, 24 cerebral infarction, 13 ischemic heart disease, 5 peripheral vessel thrombosis).

Comparator

Healthy control group (28 normal subjects)

Outcome

Correlation between platelet life-span and plasma concentration of β-thromboglobulin (β-TG) or platelet factor 4 (PF-4)surrogate

Plasma concentrations of β-TG and PF-4 are reliable indicators of intravascular platelet consumption in various diseases, including ischemic heart disease and cerebral infarction.

Cite This Study

Motoo Nagasaka (1986) studied this question.

synapsesocial.com/papers/6a94606dbeb4e1ebf564cdf8 https://doi.org/10.2974/kmj1951.36.423

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STUDY ON THE RELATIONSHIP BETWEEN PLATELET LIFE-SPAN AND PLASMA CONCENTRATION OF β-THROMBOGLOBULIN (β-TG) OR PLATELET FACTOR 4 (PF-4) IN VARIOUS DISEASE GROUPS

Discussion

Member takes

Implication

Structured PICO

Cite This Study

STUDY ON THE RELATIONSHIP BETWEEN PLATELET LIFE-SPAN AND PLASMA CONCENTRATION OF β-THROMBOGLOBULIN (β-TG) OR PLATELET FACTOR 4 (PF-4) IN VARIOUS DISEASE GROUPS

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider