Population
Adventitial fibroblasts isolated and cultured from rat thoracic aorta
Comparison
Angiotensin II for 0.5 to 24 hours, with or… vs Untreated cells or cells treated with ANG II…
Design
Preclinical
Follow-up
up to 24 hours
Authors
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Does not inform clinical practice; hypothesis-generating for epithelioid-like fibroblast targeting in vascular remodeling.
Adventitial fibroblasts are heterogeneous, and an epithelioid-like subpopulation shows high sensitivity to ANG II via the AT1 receptor, potentially implicating them in vascular remodeling.
An et al. (2015) studied this question.
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