Why the study?
Does nifedipine slow-release reduce blood pressure and improve hemodynamics in elderly hypertensive patients?
Population
n=10 non-hospitalized elderly hypertensives (WHO stage I-II), average age 73.2 years
Comparison
Nifedipine slow-release tablets 20 mg twice… vs Placebo (cross-over design)
Design
RCT, double-blind
Follow-up
8 weeks
Authors
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Supports nifedipine slow-release in elderly hypertensives; extends RCT evidence for BP control with improved cardiac output.
Does nifedipine slow-release reduce blood pressure and improve hemodynamics in elderly hypertensive patients?
Nifedipine slow-release is an effective and well-tolerated antihypertensive agent that improves cardiac output without adverse metabolic effects in elderly patients.
Landmark et al. (1985) studied this question.
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