Why the study?
Does nifedipine reduce blood pressure in patients with essential hypertension uncontrolled by a diuretic alone?
Population
24 patients with moderately severe essential hypertension, uncontrolled by a diuretic alone
Comparison
Nifedipine as a second-step drug in conjunction… vs Matching placebo in conjunction with a diuretic
Design
RCT, Double-blind
Authors
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Supports nifedipine as effective add-on for diuretic-uncontrolled hypertension; confirms its role as second-step agent in RCT evidence.
Does nifedipine reduce blood pressure in patients with essential hypertension uncontrolled by a diuretic alone?
Nifedipine is an effective second-step antihypertensive agent for patients whose blood pressure is inadequately controlled by a diuretic alone.
Haralambos Gavras (1985) studied this question.
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