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May 1, 1984Archives of Internal Medicine

Use of Nifedipine as an Adjunct to Current Antihypertensive Therapy

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Why the study?

Does nifedipine improve blood pressure control in hypertensive patients with poor responses to standard therapy?

Population

10 hypertensive patients with poor responses to standard antihypertensive therapy

Design

Case_series

Follow-up

3 to 8 weeks

Authors

MEM. EvansCaris Life Sciences (United States)

Discussion

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Implication

May support nifedipine in refractory hypertension; leaves open confirmation in randomized trials.

Structured PICO

Does nifedipine improve blood pressure control in hypertensive patients with poor responses to standard therapy?

P
Population
10 hypertensive patients with poor responses to standard antihypertensive therapy
I
Intervention
Nifedipine added to current antihypertensive therapy
O
Outcome
Blood pressure decreasesurrogate

Nifedipine is an effective adjunct for lowering blood pressure in patients with refractory hypertension.

Cite This Study

M. Evans (1984) studied this question.

synapsesocial.com/papers/6a86549edf60dc41665ae82chttps://doi.org/10.1001/archinte.1984.00350170135023

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Calcium Channel Blockers for Cardiovascular Disorders1982 · 17 citations
  2. 2Short- and long-term efficacy of a calcium-antagonistic agent (nifedipine) combined with methyldopa in the treatment of severe hypertension.1980 · 165 citations
  3. 3Hemodynamic and reflex responses to acute and chronic antihypertensive therapy with the calcium entry blocker nifedipine.1983 · 133 citations
  4. 4Nifedipine and beta-blockade as a cause of cardiac failure.1982 · 113 citations
  5. 5Captopril: Clinical Pharmacology and Benefit‐to‐Risk Ratio in Hypertension and Congestive Heart Failure1982 · 50 citations