Key result
Chewing 10-20 mg of nifedipine safely lowered BP in 61 of 63 patients with severe hypertension, with single-dose responders dropping from 205.5/127.7 to 158.6/88.8 mm Hg in 39.9 minutes.
Why the study?
Does buccal nifedipine rapidly reduce blood pressure in patients with severe hypertension?
Does buccal nifedipine rapidly reduce blood pressure in patients with severe hypertension?
Chewing perforated nifedipine capsules rapidly and safely lowers blood pressure in patients with severe hypertension without the need for parenteral medications.
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May support rapid BP lowering with chewed nifedipine in severe hypertension; leaves open need for randomized confirmation before practice change.
Jacob I. Haft (1984) studied Hypertension (n=63). Nifedipine was evaluated on Blood pressure reduction. Chewing 10-20 mg of nifedipine safely lowered BP in 61 of 63 patients with severe hypertension, with single-dose responders dropping from 205.5/127.7 to 158.6/88.8 mm Hg in 39.9 minutes.
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