Why the study?
Do calcium channel blockers reduce blood pressure in patients with essential hypertension?
Population
Patients with essential hypertension and normotensive subjects
Comparison
Calcium channel blockers (verapamil, nifedipine) vs Normotensive subjects or baseline
Design
Review
Authors
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May support greater acute BP reduction with CCBs in older patients with higher baseline values; leaves open long-term efficacy and combinations.
Do calcium channel blockers reduce blood pressure in patients with essential hypertension?
Calcium channel blockers are effective in lowering blood pressure in essential hypertension, particularly in older patients, and can be combined with beta-blockers for therapy-resistant cases.
Hulthén et al. (1984) studied this question.
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