Population
Isolated smooth muscle cells of rat portal vein
Design
Preclinical
Authors
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Should not yet inform clinical vascular therapies; leaves open whether minimal CICR and high buffering characterize human smooth muscle.
In rat portal vein smooth muscle cells, depolarization-evoked increases in intracellular calcium are tightly coupled to calcium influx through voltage-dependent channels with minimal contribution from calcium-induced calcium release.
Kamishima et al. (1996) studied this question.
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